LDH and melanoma
نویسندگان
چکیده
منابع مشابه
Melanoma inhibiting activity protein (MIA), beta-2 microglobulin and lactate dehydrogenase (LDH) in metastatic melanoma.
BACKGROUND Serum levels of melanoma markers may have a role in monitoring disease evolution in metastatic melanoma. PATIENTS AND METHODS Serial measurements of melanoma inhibiting activity protein (MIA), lactate dehydrogenase (LDH), S-100 and beta2-microglubulin were obtained from 42 metastatic melanoma patients during their biochemotherapy treatment. RESULTS High pre-treatment serum levels...
متن کاملThe Significance of Serum S100, Mia and Ldh in Cutaneous Malignant Melanoma
Malignant melanoma is a disease with a continuously increasing incidence and an unfavorable outcome in stage IV. It is a tumor with intense metabolic activity that produces and releases in the blood stream enzymes, cytokines and growth factors. Although several proteins were suggested as serum markers in malignant melanoma, until now none has proven itself sensitive enough to be currently used ...
متن کاملLong-term survival is linked to serum LDH and partly to tumour LDH-5 in NSCLC.
BACKGROUND Lactate formation is up-regulated in tumorous cells by lactate dehydrogenase (LDH). High serum LDH level is linked to many malignancies with poorer survival, but tumour LDH-5 has not been well investigated in non-small cell lung cancer (NSCLC). PATIENTS AND METHODS In 89 patients operated on for NSCLC stage I-III, the serum LDH level was assayed and immunohistochemistry for tumour ...
متن کاملDetermination of LDH isoenzymes.
THE DETERMINATION of serum lactate dehydrogenase isoenzymes holds out numerous possibilities in the clinical laboratory aside from the obvious applications in myocardial immfarction and liver disease. An excellent review on different patterims obtained in various diseases can be found in an article by Wr#{243}blewski (1). Richterich et at. (2) describe the patterns found in humami tissues. Neve...
متن کاملSerum LDH and exercise capacity in COPD.
Lactate dehydrogenase (LDH) is the enzyme that catalyses the final step in the glycolytic metabolism, regenerating NAD from reduced NADH, by conversion of pyruvate to lactate. Recently, increased muscle LDH activity has been found in elderly male patients with chronic obstructive pulmonary disease (COPD) who were susceptible to contractile fatigue of the quadriceps femoris muscle following cons...
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ژورنال
عنوان ژورنال: Cancer
سال: 1983
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19830301)51:5<840::aid-cncr2820510516>3.0.co;2-7